… ), the administration of minocycline was associated with the delay of disease progression.
In … huntingtin by minocycline and doxycycline was not associated with beneficial effects in …

… and pyruvate treatment reversed the neuronal insult produced by striatal injection of
quinolinic acid, an excito-toxic animal model of Huntington's disease. Inflammatory responses …

… readily crosses the blood-brain barrier with a rate of at least fivefold higher than doxycycline…
In one MPTP model, minocycline treatment blocked dopamine depletion in the nucleus …

… NO sufficient to cause cartilage damage (48). In cultures of cartilage cuts, doxycycline or
minocycline … In a murine model of dextran sodium sulfate-induced acute colitis, treatment with …

… dosing, with low doses being beneficial and safe [41]. Even in these pre-clinical studies it
was clear that minocycline had variable benefits in different models of neurological disorders. …

… This effect has been confirmed in experimental models of … including Parkinson's disease,
Huntington's disease, amyotrophic … as antibiotics are doxycycline and minocycline, which are …

… signaling was shown to be beneficial in an HD rodent model (98). DN… models might be
warranted to validate etanercept efficacy. … Minocycline has been shown to be protective in several …

… is not entirely understood, we herein investigated the role of immune activation in HD using
the R6/2 transgenic (Tg) HD model … However, some studies have reported that minocycline …

… Therefore we aimed to test whether minocycline protects also … model is based on the inhibitory
effect of minocycline on … Therefore, its inhibition by minocycline or doxycycline may also …

… , as shown in mouse models of Huntington disease 12 and amyotrophic lateral sclerosis (ALS).
Hereby, minocycline acts not only by … Doxycycline, which belongs to the same group as …